Kunyina musamu wakusilika bulwazi bwa Alzheimer, pesi basayaansi lyoonse bali mukuyandaula nzila zyakusilisya zitondezyo zyabulwazi oobu.
Basikuvwuntauzya alimwi bali mukubeleka kufwambaana kuzyiba bulwazi bwakubula maanu bujatikizya bulwazi bwa Alzheimer, nkaambo kufwambaana kuzyiba bulwazi oobu kulakonzya kugwasya mukusilika.
Asidi yafoomu mumulota ilakonzya kuba chitondezyo chakufwambaana kuziba bulwazi bwa Alzheimer, kweendelanya abuvwuntauzi bupya bwakasimbwa mu Frontiers in Aging Neuroscience.
Kabunga ka US Centers for Disease Control and Prevention (CDC) kapandulula bulwazi bwakubula maanu kuti "nkubula nguzu zyakuyeeya, kuyeeya, naa kusala zyakucita calo cinyonganya milimo yabuzuba abuzuba."
Mukuyungizya kubulwazi bwa Alzheimer, kuli zimwi nzila zyakubula maanu zilimbuli kubula maanu a Lewy bodies antoomwe akubula maanu kwamitsinga. Asi bulwazi bwa Alzheimer mbobulwazi bwakubula maanu buvwulide kapati.
Kweelana amalipooti aa Alzheimer's Disease Association's 2022, bantu basika ku 6.5 miliyoni mu United States bapona abulwazi oobu. Mukuyungizya, basikuvwuntauzya balangila kuti mweelwe ooyu uyooyungizigwa tubili kusikila mu 2050.
Mukuyungizya, bantu bachiswa bulwazi bwa Alzheimer balakonzya kukatazyigwa kumena, kwaambuula, akweenda.
Kusikila kumatalikilo aamyaka ya 2000, kuvwuntauzya mutunta kwakali nzila ilikke yakusinizya kuti muntu wakalijisi bulwazi bwa Alzheimer naa bulwazi bumbi bwakubula maanu.
Kweelana a National Institute on Aging, bamadokotela lino balakonzya kuchita lumbar puncture, alimwi wiitwa kuti lumbar puncture, kuti babone naa kuli zitondezyo zyabulwazi bwa Alzheimer.
Bamadokotela balalangaula zitondezyo zyabuumi zilimbuli beta-amyloid 42, cibeela chipati cha amyloid plaques mubongo, mpawo balakonzya kulangaula zintu zitali kabotu aa PET scan.
"Nzila zipya zyakufotozya, ikapati amyloid imaging, amyloid PET imaging, antoomwe a tau PET imaging, zitugwasya kubona zintu zitali kabotu mubongo muntu nachili muumi," wakaamba Kenneth M. Dr. Langa mufundisi wazyabusilisi waku Yunivesiti yaku Michigan. mu Ann Arbor, ooyo watakali kujatikizyidwe mukwiiya, wakaamba aatala a Michigan Medicine podcast.
Zimwi nzila zyabusilisi zilakonzya kugwasya kuchesya bupati bwazitondeezyo zya asthma akulesya kuyaambele kwabulwazi, nikuba kuti tazikonzyi kubusilika.
Mbuli chitondeezyo, dokotela ulakonzya kulemba misamu iili mbuli donepezil naa galantamine kuti ichese zitondezyo zya asthma. Musamu wakuvwuntauzya wiitwa kuti lecanemab ulakonzya kuchesya kuyaambele kwabulwazi bwa Alzheimer.
Nkaambo kakuti kulanga-langa bulwazi bwa Alzheimer kuladula alimwi inga tiikwajanwa kubantu boonse, bamwi basikuvwuntauzya babikka kumbele kulanga-langa bulwazi bwa Alzheimer.
Basikuvwuntauzya kuzwa ku Shanghai Jiaotong University antoomwe a WuXi Institute of Diagnostic Innovation of China bakavwuntauzya antoomwe mulimo wa formic acid mbuli chitondezyo cha Alzheimer's disease mumulota.
Basayaansi bakasala musamu ooyu kweendelanya aziiyo zyakachitika musule zyabulwazi bwa Alzheimer. Baamba kuti kutabeleka kabotu kwa formaldehyde nchintu chipati chipa kuti muntu achembeede.
Kuchiiyo eechi, balembi bakabweza bantu bali 574 kuzwa kuchipatara cha Memory cha Sixth People's Hospital yaku Shanghai, China.
Bakaandaanya basikutola lubazu muzibeela zyosanwe kweendelanya akuti bakachita biyeni mumasunko aakubeleka kwabongo; tubunga ootu twakali kuzwa kukuyeeya kubotu kusikila kubulwazi bwa Alzheimer:
Basikuvwuntauzya bakabweza misamu ya minsyu kuzwa kuli baabo bakatola lubazu kuti babone naa kuli asidi ya formic alimwi abulowa bwakuvwuntauzya DNA.
Kwiinda mukweezyanisya mweelwe wa asidi ya formic mukabunga kamwi akamwi, basikuvwuntauzya bakajana kwiimpana aakati kabaabo bajisi boongo kabotu abaabo bajisi penzi lyakuyeeya.
Mutubunga twabantu bakajisi kucheya kwakuyeeya, mweelwe wa asidi mumulota wakali mupati kwiinda tubunga twabantu bakajisi boongo buli kabotu.
Mukuyungizya, aabo bakatola lubazu bachiswa bulwazi bwa Alzheimer bakalijisi asidi mupati loko mumulota wabo kwiinda aabo bakatola lubazu bajisi boongo.
Basayaansi bakajana kuti kuli kujatana kutali kabotu aakati ka asidi ya formic mumulota akusunkwa kwakuyeeya mumbazu zyakuyeeya akubikkila maanu.
"UA yakasumpulwa kapati mukabunga ka [kucheya kwakuyeeya], eezi zyaamba kuti UA ilakonzya kubelesegwa kufwambaana kuzyiba [bulwazi bwa Alzheimer]," balembi bakalemba.
Zyakazwa mukwiiya ooku zilayandika nkaambo katwaambo tunji, kutali buyo amali manji aakujana bulwazi bwa Alzheimer.
Kuti buvwuntauzi bumbi bwatondezya kuti minsyu ilakonzya kujana kucheya kwakuyeeya, eechi chinga chaba nzila nguba yakubelesya alimwi iitaduli pe.
Mukuyungizya, ikuti musunko uliboobu wakonzya kujana kucheya kwakuyeeya kweendelana abulwazi bwa Alzheimer, basyaazibwene mumulimo wabusilisi balakonzya kugwasya chakufwambaana.
Dr. Sandra Petersen, DNP, mupati wabili wabweendelezi bwabuumi abukkale bubotu ku Pegasus Senior Living, wakaambila Medical News Today aatala achiiyo:
"Kuchincha kwabulwazi bwa Alzheimer's kutalika myaaka iili 20 kusikila ku 30 kakutanajanwa mpawo kanjikanji takubonwi kusikila kwaba kunyonyooka kupati. Tulizi kuti kufwambaana kubuzyiba kulakonzya kupa kuti bachiswa bajane nzila zyiingi zyakusilikwa akukonzya kulibambila busilisi bwakumbele."
"Kuzwidilila munzila eeyi (iitabelesyi misamu iikola alimwi iitaduli) iikonzya kujanwa abantu boonse inga yaba chintu chipati mukulwana bulwazi bwa Alzheimer," Dr. Peterson wakaamba.
Basayaansi lino-lino bakajana chintu chikonzya kugwasya bamadokotela kuti bazyibe bulwazi bwa Alzheimer kakuchili chiindi. Eezi ziyoozumizya basilisi...
Zyakajanwa zipya mu mbeba zilakonzya kugwasya kupanga nzila yakusunka bulowa eeyo iyooba cibeela chakupima bulwazi bwa Alzheimer's azimwi zilwazi...
Buvwuntauzi bupya bubelesya PET brain scans kuyeyela kucheya kwakuyeeya kweendelanya akujanika kwa amyloid antoomwe a tau proteins mubongo, aakati kazyintu zimwi zyakuyeeya...
Basilisi lino babelesya nzila zyakusunka boongo ziindene-indene akupima bulwazi bwa Alzheimer. Basikuvwuntauzya bakapanga nzila iikonzya kubelesegwa kuli...
Kulangisisya meso chakufwambaana kulakonzya kupa makani aayandika aatala abuumi bwabongo. Ikapati, ilakonzya kubona zitondezyo zyakubula maanu.